A partial list of disorders that have responded within 2 visits

PhotoMed's team sponsored and supported feasibility studies for the variable-wavelength therapy. The responses and outcomes to the therapy exceeded everyone's imagination. The answer was overlooked for years.

A primary reason for skepticism was (and still is) that the team found no predictions of the observed responses and outcomes in tomes on chronic pain.


How could unrelenting "unmanageable" chronic pain simply vanish? It would take nearly 20 years to find the solution --> in the language of rehabilitation. The practitioner uses non-invasive devices aimed to prompt the body to resume its normal healing.  The measure of success, normal functioning, is easy to detect when completed - the patient doesn't need more therapy.

The founder and funder of the studies is a skeptical mechanical engineer. He led the team to utilize industrial strategies for testing the new therapy while collecting real-time data. PhotoMed's team invented sophisticated recording system is called the Instant Verification System to help make the therapy more efficient.

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Objective measures (sensory, motor, skin temperature, & wounds) and TIME provided comparative data for improving the therapeutic efficiency. Like a nature video or video referee, you can watch as the stimulation prompts a physiological response and beneficial outcome. Preferably, the impaired functioning is a diagnostic sign rather than a biomarker or surrogate endpoint.

Attempts failed to quantify possible wavelength-dose-response relationships for abnormally cold hands or feet. The problem was that there were 300 wavelengths to test. Worse, the dose calculations didn't compute when NO more therapy was needed. It now appears that the body had received the right signal to restart its normal functioning or healing.

Another challenge for studying non-invasive therapies is that the body continues with its own healing after the therapy ends. The responses may be indistinguishable from "normal" except for the months or years of delay. Could it be the delay and unexpectedness that makes the responses seem special?

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The team's attempts failed to find a conventional dose-response explanation for the recorded responses and outcomes. The people who enrolled in the feasibility studies had typically exhausted conventional technologies without achieving long-term improved functioning.

The physical rehabilitation model solves the mystery with the therapeutic aim to restore normal functioning. Non-invasive therapies prompt ordinary healing processes to resume or accelerate. We call these outcomes the return to normal functioning (R2N).

The vertical axis of Costs illustrates the savings from the R2N events. This website shows examples of the R2N for the sensory, motor, skin temperature, and wound healing systems. The term R2N unifies the responses and outcomes as a confirmation that ALL of the systems need to be working and coordinated for wellness to resume.

The concern for some practitioners is that their waiting room will empty. Some practitioners suggest that the R2N works more like a winning slot machine in Las Vegas. The people with unmanageable chronic pain seldom arrive with only one source of pain or impairment. Recorded data suggest that only one or two impairments return to fully normal. The other impaired functions may feel better but not fully normal. We don't know why. Our mission focuses on those who remain underserved by current technologies.

Serving patients who endure "unmanageable" chronic pain

The team specifically asked researchers to reduce selection bias by primarily inviting their patients with long duration and high-impact pain for whom nothing had worked before. Traditional pain studies that aim to confirm a hypothesis may intentionally exclude  people that aren't expected to respond to the intervention.

PhotoMed's team intentionally invited people with the "unmanageable", "treatment-resistant" or "nothing works" types of pain. These unfortunate people were enrolled with no reasonable expectation of improved functioning. These zero-expectation "controls" responded by returning to normal functioning while being documented by the recording system. Should the expectation remain zero now that the responses have been shown?


The previously failed interventions provided randomized "control arms" to test the null hypothesis: "the new therapy will not provide greater relief than any previous intervention". At the beginning, no one (including the founder and team) expected that the therapy might "work" for so many seemingly disparate disorders.

The engineers focused on quick events that could be measured during a single visit without the person leaving the room. With their permission, the entire visits were recorded, sections were cropped and shown on this site. Researchers may watch the extended recordings via Zoom upon request.

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Patterns emerged from the data surrounding Quick Events. Many, possibly most, events involved the whole body. Like many wellness therapies, both hands warm and return to normal functioning (interventions such as a nerve block shuts off thermoregulation in a single limb. See the skin temperature page.

The Quick Events appear to challenge notions about the loss of sensation and how sensations resume. For example, the pervasive notion that the feet won't awaken after years of "sleeping".

An exemplary case, "George" showed that sensations in BOTH of his feet can resume so quickly that his skin-touch-location maps are not aligned with his feet. His feet had been off-line for 8 years, possibly as a side effect from 40 years of diabetes. Volunteers were asked if it would be okay if their "before numb" pain returned along with improved sensations. Only one person opted out.

The quick-event functional-level responses and outcomes suggest new areas of research that may be economically achieved using the Instant Verification System.

Reproducing the return to normal functioning


More than 500 people volunteered in the feasibility studies at 7 sites (California [2], Massachusetts, Colorado, Pennsylvania [2], Florida). Many participants arrived with multiple sites of unresponsive functions and pain. Reviews of study data suggest that many volunteers received physical medicine and rehabilitation (PM&R) therapies that had not provided long-lasting relief or improved functioning.

Today, it appears that the people who have had their pain adequately "managed" by pain-masking interventions do not respond with quick events or fully return to normal functioning. However, they may report feeling "better" but few would report that they "feel normal again".

Practitioners may recognize similar responses and outcomes from other non-invasive therapies. That should be unsurprising because lots of different "alarms" can awaken sleeping functioning.

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Doesn't the return to normal functioning describe the basic program of life itself?

Note that the focus is on impaired functioning. The practitioner derives feedback from the diagnostic sign that is impaired. For example, cold hands, loss of sensation, loss of movement, and non-healing wounds.

Our mantra is a corollary to Lord Kelvin's quote: You can improve only that which you can objectively measure.


A partial list of impaired functions that have responded within 2 visits

Please set aside your feelings of "that healing can't happen". "Awakening" a sleeping function provides a basic framework for examining events that don't appear logical from a "need another dose" perspective.

Each photon that stimulates the skin deposits it's energy and exists no more after less than a trillionth of a second. The body heals itself; the therapy prompts a restart. Please feel free to share other ideas - we are engineers seeking the simplest model to communicate what might be happening.

Different from a medication or spinal cord stimulation, the photons aren't present to "manage" any improved functioning or to hide pain. Non-invasive therapies may work more like a jump-start of a stalled car: once restarted, the car runs normally.


Photon-based therapies may momentarily bring the body's healing focus to the stimulated area. That attention may then prompt the stalled processes to resume their ordinary functioning.

Note that the disorders and diseases list are for ease of identification only. The return to normal functioning does NOT treat the disease or disorder. For example, the return of normal sensation does NOT relieve diabetes or end diabetic neuropathy. The methods of exclusion suggest that two or more problems are co-located: the disorder and the impaired ordinary function.

PhotoMed's feasibility studies welcomed people without exclusion for the duration, intensity, or type of impairments. The principal investigators welcomed their own patients having a long history of failed attempts with previous technologies.

The purpose of the studies was to find boundaries for possible conditions that might respond to the then experimental therapy. The team slowly adjusted its perspective from treating a disease to prompting ordinary, but stalled, functions to resume. Self-healing is the function that distinguishes living things from dead ones.

Without healing, wellness remains elusive. The body heal itself; the variable-wavelength only prompts a restart (or acceleration) of healing.

Would the Quick Events be noticed if healing had finished on schedule?

Sensory impairments

  • Loss of sensation in fingers or toes

  • Diabetic peripheral neuropathy (DPN)

  • Complex regional pain syndrome (CRPS or RSD)

  • Post-surgical pain

  • Post-chemotherapy pain

  • Neuropathy from other causes, such as stroke or spinal cord injury

  • Sympathetically mediated (or maintained) pain

  • Post-herpetic pain (shingles)

  • Phantom pain in missing limbs and reconstructed skin

  • Mirror-neuron synesthesia

  • Headaches

Motor impairments

  • Loss of grip strength and movement

  • Muscle knots

  • Arthritis

  • “Frozen” joint movements

  • Lost range-of-motion

  • Loss of movement after stroke or spinal cord injury (therapy helps overcome “learned” non-use)

  • Carpal tunnel syndrome

  • Scoliosis

  • Loss of coordination in gait & swallowing, and choreic movements from Huntington’s disease

  • Bell's Palsy

  • Headaches

Autonomic abnormalities

  • Abnormally cold or hot hands, with or without pain

  • Abnormal sweating

  • Thermoregulation, gut, bowel, and bladder function after spinal cord injury

  • Complex regional pain syndrome (CRPS or RSD)

  • Raynaud's syndrome

  • Headaches


  • Restart non-healing wounds at any stage

  • Accelerate slow-healing wounds

  • Diabetic foot ulcers and loss of sensation

  • Venous stasis ulcers, bed sores (pressure injuries or pressure ulcers)

  • Improve scars, keloids


The terms "treatment resistant", "unmanageable", and "nothing works" refer to pain and impairments that persist after conventional interventions failed to provide lasting relief. Injuries that may be adequately "managed" typically do not appear to respond with a return to normal functioning. That is, the "unmanageable" and "managed" groups appear to include different people.

The body heals itself; the therapy prompts a restart.

Disclaimer: The responses listed on this website are based upon data collected during development of PhotoMed’s products. The methods, Vari-Chrome® Pro, and Instant Verification System™ are not intended to diagnose, treat, cure, or prevent any disease. The term “normal” refers to a functional state maintained by the body in the absence of a medication or therapy. The term "healing" refers to the transitional processes between the injury and the restoration of normal functioning.